Helicobacter pylori infection. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention 1: Intervention group: Levofloxacin 500 mg daily, amoxicillin 1 g twice daily and omeprazole 20 mg twice daily for 10 days, then omeprazole 20 mg daily for 4 weeks. Intervention 2: Contro
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Confirmation of the presence of H.pylori by fecal antigen test
Exclusion criteria
Exclusion criteria: History of previous treatment for eradication of Helicobacter pylori Age less than 18 years and over 65 years History of allergy or severe reaction to drugs used in the plan History of major surgery on the gastrointestinal tract such as bilirut and bypass and gastrogenostomy And gastrectomy Severe underlying disease such as liver failure) Cirrhosis of the liver (or kidney) Creatinine above 2 (or proven malignancy Untreated active Active pregnancy or lactation Inability to follow up Use of proton pump inhibitors And antibiotics in the last 4 weeks Contraindications to the use of prescription drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Negative stool antigen test for Helicobacter pylori infection at the end of treatment. Timepoint: 2 months and 10 days after starting treatment. Method of measurement: Stool antigen test for Helicobacter pylori infection. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adherence to treatment. Timepoint: 11 days after starting treatment. Method of measurement: questionnaire.;Complications of treatment. Timepoint: 11 days after starting treatment. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohamad Taher
Tehran University of Medical Sciences
Outcome results
None listed