Evaluation of the effect of norepinephrine, ephedrine and phenylephrine in treatment of hemodynamic changes in spinal anesthesia in Caesarean section surgeries

Evaluation of the effect of norepinephrine, ephedrine and phenylephrine on prophylaxis and treatment of hemodynamic changes of spinal anesthesia in elective Caesarean section surgeries

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210204050243N1

Enrollment

Registered

2021-05-07

Start date

2021-03-21

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic changes of spinal anesthesia. Spinal and epidural anesthesia-induced headache during labor and delivery

Interventions

Intervention 1: Intervention group 1 : Right after spinal anesthesia is done 5 micrograms of norepinephrine will be administered then the patient’s vital signs will be documented every one minute till

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patient consent Gestational age >36 wks Height>150 cm Age 18 -40 years Weight 60 kg - 80 kg

Exclusion criteria

Exclusion criteria: Spinal block failure Preeclampsia History of hypertension Gestational age of < 36 wks Multiple gestation Height < 150 cm Opium addiction Contraindication of spinal anesthesia History of heart disease Patient discontent

Design outcomes

Primary

Measure	Time frame
The percentage of women with low blood pressure and heart rate. Timepoint: Right after basic monitoring then every one minute right after the spinal anesthesia is done till the birth and then every five minutes till the end of the surgery. Method of measurement: Blood pressure monitor and pulse oximeter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRima Alghozat

Iran University of Medical Sciences

rimaghozat1989@yahoo.com+98 21 2214 7094

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026