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Comparison of the results of treatment of the primary parathyroid adenoma with surgery or ablation with ethanol.

Comparative effectiveness of treating primary hyper-parathyroid patients due to parathyroid adenoma with parathyroidectomy versus ultrasonography-guided alcohol ablation

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210204050241N1
Enrollment
120
Registered
2021-04-26
Start date
2021-05-05
Completion date
Unknown
Last updated
2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign parathyroid adenoma. Benign neoplasm of parathyroid gland

Interventions

Intervention 1: Intervention group 1: Classic surgical resection of parathyroid adenoma with a neck incision. Intervention 2: Intervention group 2: After complete neck ultrasonography with doppler, th

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 50 Years

Inclusion criteria

Inclusion criteria: Patients with symptomatic benign parathyroid adenoma confirmed by ultrasound, MIBI scan, and fine needle aspiration

Exclusion criteria

Exclusion criteria: Patients with MEN1 or MEN2 syndrome Patients with suspected parathyroid malignant adenoma Patients with secondary or tertiary hyperparathyroidism Not willing to participate in the trial GFR<30 ml/min/1.72 m2 age above 50

Design outcomes

Primary

MeasureTime frame
Serum calcium level. Timepoint: Before the intervention, 24 hours, two weeks, three months, and six months after the intervention. Method of measurement: Blood sample tests.;Serum PTH level. Timepoint: Before the intervention, 24 hours, two weeks, three months, and six months after the intervention. Method of measurement: Blood sample tests.

Secondary

MeasureTime frame
Adenoma recurrence (reoperation or re-injection of alcohol). Timepoint: Within 3 months and 6 months after the intervention. Method of measurement: Changes in serum calcium and parathyroid hormone levels after intervention.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Firoozfar

Esfahan University of Medical Sciences

alireza.firoozfar@resident.mui.ac.ir+98 31 3236 5742

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026