Plasma-rich platelet veruss carboxytherapy for the treatment of periocular hyperpigmentation

Plasma-rich platelet veruss carboxytherapy for the treatment of periocular hyperpigmentation; which approach is superior?

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210130050181N1

Enrollment

Registered

2021-02-13

Start date

2021-02-08

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periocular hyperpigmentation.

Interventions

Intervention 1: Intervention group: Carboxytherapy was performed by injection of carbon dioxide gas once weekly for six weeks. The amount of 5cc of CO2 was intradermally injected at the one-third late

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 3-4 Fitzpatrick skin type Age 20-65 years old

Exclusion criteria

Exclusion criteria: History of internal medical diseases(e.g., no previous history of cardiac, liver and/or renal diseases, diabetes mellitus, and thyroid dysfunction History of platelet disorders and/or coagulopathy Smoking and/or addiction Lactating or pregnancy Patients' unwillingness of participation in the study Use of other therapeutic approaches

Design outcomes

Primary

Measure	Time frame
Score of periocular hyperpigmentation. Timepoint: Before and within eight weeks after study performance. Method of measurement: Visual analog scale score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAkram Sadat Amiri

Esfahan University of Medical Sciences

sadstamiri1367@Gmail.com+98 31 3653 3805

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026