periorbital wrinkle, dark circle and puffiness. Changes in skin texture
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Male or female aged 18-59 years Signed informed consent knowingly The presence of mild to moderate periorbital wrinkle and darkness
Exclusion criteria
Exclusion criteria: Using any eye product within 2 weeks before the intervention Strict diet in the period of 2 weeks before the intervention Pregnancy or lactation Being exposed to strong sunlight during the day
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of under eye dark circle and wrinkle. Timepoint: Before intervention and 6 and 28 days after treatment. Method of measurement: Based on GIAS(Global Aesthetic Improvement Scale). | — |
Secondary
| Measure | Time frame |
|---|---|
| Melanin content. Timepoint: fore intervention and 6 and 28 days after treatment. Method of measurement: Mexameter.;Infra-orbital pigmentation severity and degree of lightness. Timepoint: fore intervention and 6 and 28 days after treatment. Method of measurement: Visioface. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences