periorbital wrinkle, dark circle and puffiness.
Conditions
Interventions
Intervention group: Using Synskin triple action eye contour cream twice a day for 8 weeks.
Sponsors
Iran Avandfar Company
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Male or female aged 30-60 years The presence of periorbital wrinkle, dark circle and puffiness No change in life style during the study Signed informed consent knowingly
Exclusion criteria
Exclusion criteria: Critical untreated systemic disease in medical history Any facial rejuvenation treatment, including treatment with topical or oral products or supplements during the last four weeks Any facial rejuvenation treatment including rejuvenation devices or surgical procedures and Botox injections during the last four months Sensitivity and allergy to the components of the formulation Use of any eye cream or eye sunscreen cream during the last four weeks Use of anti-wrinkle or brightening cleansers over the past four weeks Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of periorbital wrinkle, dark circle and puffiness by three independent physician using 0-3 scale. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Three independent dermatologists perform evaluation and scoring with the help of right and left lateral view and full face photos based on the percentage of improvement in periorbital wrinkles, dark circle and puffiness using scale 0 to 3 (0 = no improvement 1 = relative improvement 2 = good improvement 3 = Excellent improvement) . | — |
Secondary
| Measure | Time frame |
|---|---|
| Area, volume and depth of periorbital wrinkle. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Visioface.;Periorbital dark circle grading using Characteristics of Dark circles grade. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Research physician will perform clinical assessments according to the Characteristics of Dark circles grade.;Melanin content. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Mexameter.;Stratum corneum hydration. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Corneometer.;Trans epidermal water loss. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Tewameter.;Erythema. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Mexameter.;Fitzpatrick’s Classification of Facial Wrinkling & degree of Elastosis. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Research physician will perform clinical assessments according to the Fitzpatrick’s Classification.;Infra-orbital pigmentation severity and degree of lightness. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Visioface. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTaraneh yazdanparast
Tehran University of Medical Sciences
Outcome results
None listed