The effect of topical magnesium sulfate on the cervix in the development of labor

The effect of topical magnesium sulfate compared with topical normal saline on the cervix in the progression of labor : a randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210127050156N2

Enrollment

200

Registered

2021-12-06

Start date

2021-12-22

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

labor. ----

Interventions

Intervention 1: Intervention group:They will received 5 cc magnesium sulfate 50%, topically on the cervix in the latent and also in the active phase of labor. Intervention 2: Control group: The

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Pregnant woman candidate for vaginal birth primigravid gestational age>= 38 weeks

Exclusion criteria

Exclusion criteria: Indications for cesarean section include failure to progress, cessation of labor, decreased heart rate, bleeding and cleft palate, placenta abruption , fever, and chorioamnionitis Underlying diseases such as diabetes and hypertension Preeclampsia Eclampsia

Design outcomes

Primary

Measure	Time frame
Duration of labor. Timepoint: After delivery. Method of measurement: Stopwatch.;Bishop Score changes. Timepoint: Every two hours until delivery. Method of measurement: Score Bishop Curve.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoumeh Farahani

Karaj University of Medical Sciences

m.farahanii@abzums.ac.ir+98 21 2236 5627

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026