evaluation of the effect of duloxetine in reducing pain

Evaluation of the Perioperative and Postoperative effects of Duloxetine in reducing postoperative pain in patients with spinal stenosis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210124050130N1

Enrollment

Registered

2021-08-07

Start date

2021-06-26

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Evaluation of the Perioperative and Postoperative effects of Duloxetine in reducing postoperative pain in patients with spinal stenosis. Spinal stenosis

Interventions

Intervention 1: Intervention group: will receive 60 mg of oral duloxetine daily for 1 day before surgery, 60 mg daily from the day of surgery to the first day after surgery (total 3 days). Interventio

day of surgery

one day after surgery.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: all patients with spinal stenosis

Exclusion criteria

Exclusion criteria: Allergy to the test drug Abnormal liver and kidney function test Use of opioids, gabapentin and pregabalin for more than three months

Design outcomes

Primary

Measure	Time frame
Numeric rating scale according to visual analogue scale. Timepoint: visual analogue scale before surgery and 2 hours after surgery and 24 hours after surgery. Method of measurement: by visual analogue scale criterion.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMitra Shahriary poor

Islamic Azad University

mitrashahriary143@gmail.com+98 34 4225 7756

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026