Evaluation of the effect of bisoprolol in the control of atrial fibrillation

Evaluation of the effect of oral Bisoprolol in comparison with oral Metohexall in prevention of atrial fibrillation in coronary artery bypass graft (CABG)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210121050095N1

Enrollment

114

Registered

2021-05-19

Start date

2020-08-26

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial fibrillation in patients undergoing coronary artery bypass grafting. Atrial fibrillation and flutter

Interventions

Intervention 1: Intervention. Patients received bisoprolol orally with the initial dose 2.5 mg one day before surgery to 3 days postoperatively based on heart rate, blood pressure, and ECG. Intervent

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients with coronary heart disease are candidates for coronary heart surgery

Exclusion criteria

Exclusion criteria: History of previous atrial fibrillation Having a permanent pacemaker Any conclusive evidence of any ventricular or supra ventricular arrhythmia Large left ventricle Moderate to severe valvular heart disease myocardial infarction Lung disease

Design outcomes

Primary

Measure	Time frame
Incidence of atrial fibrillation after coronary artery surgery. Timepoint: Up to four days after coronary artery surgery. Method of measurement: How to diagnose and measure atrial fibrillation using ECG based on p's presence and irregularity of QRS and QRS count.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeid Negahdar hadadan

Qazvin University of Medical Sciences

S.negahdar@qums.ac.ir+98 28 3333 2930

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026