Cholecystitis. Cholecystitis, unspecified
Conditions
Interventions
Intervention 1: Intervention group: prescription of one tablet atorvastatin 40 mg (?Dr Abidi Factory) daily for 6 weeks. Intervention 2: Control group:Prescription of one tablet placebo (such as atorv
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -Patient satisfaction -patients for interval cholecystectomy
Exclusion criteria
Exclusion criteria: patient dissatisfaction several background problems such as cardiovascular pulmonary etc who are not operable and should done cholecystostomy for them previous use of atorvastatin for cardiovascular diseases and dyslipidemia atorvastatin use contraindications:drug hypersensitivity reactions pregnancy active hepatitis liver ensymes elevation breastfeeding women distinguished by specialist and not entered into research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement clinical and paraclinical scale of patients with cholecystitis. Timepoint: everyday during hospital stay history and physivcal exam CBC CRP LFT before and after study or CBC CRP check every 3 days during hospital stay and LFT if drug induced hepatotoxicity is detected. Method of measurement: fever=>termometer pain nausea=>ask of patient hospital stay and operation time and intraoperation bleeding =>patient documents visual analogue scale inflamatory response=>pathological biopsy of gallbladder CBC CRP. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital stay and operation time. Timepoint: day 7, 14 ,21, 42, 49. Method of measurement: visual analogue scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMasood Nezamdoost
Birjand University of Medical Sciences
Outcome results
None listed