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Comparison of buccal patches containing lidocaine and dexmedetomidine with articaine and dexmedetomidine in dental procedures

Preparation and comparison of buccal patches containing lidocaine and dexmedetomidine with articaine and dexmedetomidine in reduction of injection pain and increment of patients compliance in dental procedures

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210118050067N2
Enrollment
180
Registered
2022-08-19
Start date
2022-08-23
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain caused by local anesthetic injection.. Other dental procedure status

Interventions

Intervention 1: Intervention group: Patients in this group receive a patch containing 350 mg of lidocaine. Intervention 2: Intervention group: Patients in this group receive a patch containing 350 mg

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Patients should cooperate for the study. Visiting for dental services that require local anesthesia.

Exclusion criteria

Exclusion criteria: Those with any systemic disease (cardiovascular disease, diabetes, etc.), physical and mental illness. Patients who have a history of taking any painkillers and corticosteroids in the last week. Patients who have allergy to lidocaine and articaine. Patients who have dental phobia. Patients who have inflammation, abscess, and history of surgery at the injection site.

Design outcomes

Primary

MeasureTime frame
Pain caused by injection. Timepoint: 20 minutes after lidocaine injection. Method of measurement: After finishing the procedure, we ask the patients to mark the pain they experienced on the Visual Analogue Scale from 0 to 10.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMilad Etemadi

Esfahan University of Medical Sciences

etemadi@dnt.mui.ac.ir+98 31 3792 5581

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026