Actinic keratosis. Actinic keratosis
Conditions
Interventions
Intervention 1: Control group: Patients take 5% 5-fluorouracil cream from Meda Co. They take the cream every night until the next morning for 4 weeks. Intervention 2: Intervention group: Patients take
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Clinical diagnosis of actinic keratosis at least 18 years old consent of the individual to participate in the study
Exclusion criteria
Exclusion criteria: Previous history of allergy to formulation ingredients pregnant or lactating mothers patients on immunosuppressive, immunomodulatory, cytotoxic, and systemic steroid drugs patients who received treatment for their lesions in the 4 weeks preceding the study patients with lip lesions (because of prevention of changing into Squamous cell carcinoma)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment of cutaneous lesions. Timepoint: at the beginning and after 6 weeks. Method of measurement: Global improvement score.;Patient satisfaction. Timepoint: 6 weeks after starting the use of nanofibers and Fluorouracil cream. Method of measurement: Visual Analogue Scale Score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects. Timepoint: 6 weeks after starting the use of nanofibers and Fluorouracil cream. Method of measurement: Ask the patient and Physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNazila Poostiyan
Esfahan University of Medical Sciences
Outcome results
None listed