chronic kidney disease. Chronic kidney disease, stage 4 (severe)
Conditions
Interventions
Intervention 1: Intervention group: Intervention: Recipient of Lactococare synbiotic dietary supplement capsule (500 mg) containing 12 beneficial bacterial(Lactobacillus rhamnosus, Lactobacillus holot
Sponsors
Sabzevar University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: A patient with a diagnosis of chronic kidney disease who undergoing hemodialysis for at least 3 months. signing informed consent for participation in the study Patient with arteriovenous fistula or permanent catheter or venous arterial graft The patient undergoing hemodialysis 3 times a week for 4 hours each time Patient with KT / V> 1 Do not suffer from hearing and vision disorders No neurological disorders and a history of hospitalization in the psychiatric ward age range of 18 to 65 years
Exclusion criteria
Exclusion criteria: Active infection during the last 30 days Pregnant or lactating mothers Taking antibiotics, prebiotics, probiotics, synbiotics, vitamin supplements or antioxidants during the last 30 days Suffering from autoimmune diseases or connective tissue disorders History of cardiovascular diseases Diabetic foot infection Gastrointestinal diseases (inflammatory bowel disease, ulcerative colitis, Crohn's disease, celiac disease, lactose intolerance or allergy, irritable bowel syndrome) Liver disease (such as hepatitis B, hepatitis C) suffering from various types of malignancies Smoking more than 10 cigarettes per day Participate in other drug interventions hemoglobin less than 8 mg/dl PSQI score less than 6 (good sleep quality) acquisition of CFS score less than 18
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue. Timepoint: 2 months. Method of measurement: Chalders Fatigue Scale.;Sleep quality. Timepoint: 2 months. Method of measurement: Pittsburgh Sleep Quality Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMina Jangpoor
Sabzevar University of Medical Sciences
Outcome results
None listed