Effect of vitamin D in treatment of burn

The effect of vitamin D supplementation on inflammation and antioxidant markers in the burned hospitalized patients

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210116050044N1

Enrollment

Registered

2021-03-08

Start date

2021-01-20

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn of second degree of trunk, unspecified site. Burn of second degree of trunk, unspecified site

Interventions

Intervention 1: Intervention group: Vitamin D3 is produced in the form of a tablet with a dose of 2000 international units by Darsa Daru Pharmaceutical Company and is recommended for 8 weeks a day (o

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: people between the ages of 18-60 patients with secondary degree burns with a burn level between 20%-50% Vitamin D <30 ng/ml lack of supplementation vitamin D during the last three months No history underlying diseases including Kidney, Diabetes, hyperthyroidism and other metabolic diseases No pregnancy and breastfeeding

Exclusion criteria

Exclusion criteria: lack of cooperation participators with project facilitators during this study diagnosis of another chronic disease during this study Each patient can be excluded from the study at any stage if he/she is not satisfied with the study

Design outcomes

Primary

Measure	Time frame
The amount of vitamin D through ELISA test is measured in ng/l. Timepoint: Measurement of vitamin D will be at the beginning of the study (before the intervention) and after the intervention. Method of measurement: The measure of variable is done by ELISA method.	—

Secondary

Measure	Time frame
Inflammatory factor CRP is measured by photometric enriched turbidolatex method. Timepoint: The variable is measured at the beginning of the study (before the intervention) and after the intervention at the end of the study. Method of measurement: The measurement is done based on the CRP vial.;Antioxidant factors are measured in terms of ng / L based on ELISA method. Timepoint: The variable is measured at the beginning of the study (before the intervention) and after the intervention at the end of the study. Method of measurement: The method of measuring antioxidant factors by ELISA kit.	—

Measure

Time frame

Inflammatory factor CRP is measured by photometric enriched turbidolatex method. Timepoint: The variable is measured at the beginning of the study (before the intervention) and after the intervention at the end of the study. Method of measurement: The measurement is done based on the CRP vial.;Antioxidant factors are measured in terms of ng / L based on ELISA method. Timepoint: The variable is measured at the beginning of the study (before the intervention) and after the intervention at the end of the study. Method of measurement: The method of measuring antioxidant factors by ELISA kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFahimeh Beigi

Esfahan University of Medical Sciences

f.beigi@mail.mui.ac.ir+98 31 3668 0048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026