The evaluation of the effect of COVID-19 vaccination on calprotectin levels in IBD patients

The evaluation of the effect of COVID-19 vaccination on calprotectin levels in IBD patients: A quasi-experimental study

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210113050024N3

Enrollment

Registered

2021-09-16

Start date

2021-10-22

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory Bowel Disease. Other and unspecified noninfective gastroenteritis and colitis

Interventions

Intervention group: Patients with intestinal inflammation who receive the first dose of the Covid-19 vaccine..

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: The IBD patients Willing to cooperate in completing the questionnaire and secondary follow-up Be over 18 years old.

Exclusion criteria

Exclusion criteria: Patient non-cooperation The patient is in a state of recurrence and has symptoms of bleeding and fever during this period

Design outcomes

Primary

Measure	Time frame
Fecal chlorprotectin levels. Timepoint: The calprotectin level is checked one to fifteen days before the Covid-19 vaccination and also two weeks and twelve weeks after receiving the vaccine. Method of measurement: Fecal calprotectin levels are assessed using ELISA kits.;Illness severity. Timepoint: One to fifteen days before the Covid-19 vaccination and two weeks and twelve weeks after receiving the vaccine. Method of measurement: Lichtiger and Mayoscore questionnaire.	—

Measure

Time frame

Fecal chlorprotectin levels. Timepoint: The calprotectin level is checked one to fifteen days before the Covid-19 vaccination and also two weeks and twelve weeks after receiving the vaccine. Method of measurement: Fecal calprotectin levels are assessed using ELISA kits.;Illness severity. Timepoint: One to fifteen days before the Covid-19 vaccination and two weeks and twelve weeks after receiving the vaccine. Method of measurement: Lichtiger and Mayoscore questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactBabak Tamizifar

Esfahan University of Medical Sciences

babaktamizifar@gmail.com+98 31 3822 2675

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026