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The effect of atorvastatin administration on the outcome of patients with traumatic brain injury

The effect of Atorvastatin administration on the outcome of patients with traumatic brain injury

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210113050023N1
Enrollment
60
Registered
2021-05-31
Start date
2021-04-03
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Injury. Unspecified brain damage due to birth injury

Interventions

Intervention 1: Intervention group: In the intervention group, in addition to receiving routine care (daily intake of vitamins C and D and E and regulation of sodium, calcium and potassium electrolyte

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with moderate (GCS = 9.13) and severe (GCS = 8.5) brain trauma injuries based on GCS score Patients with size of brain contusions less than 30 CC according to the initial CT-scan of the brain No history of statins Patients who arrived at the hospital less than 10 hours after the injury their legal representative (guardian or trustee) will be present to receive the consent

Exclusion criteria

Exclusion criteria: Patients with GCS scores of 4 and 3 Patients with Grade IV on primary brain scan or CT scan Patients with severe damage to other internal organs or spinal cord injury History of kidney or liver disease Creatine>2.5 mg/dl History of brain tumor, stroke History of infection Previous craniotomy Pregnant and lactating women Patients with systolic blood pressure less than 90 mm Hg History of taking low-molecular-weight anticoagulants such as aspirin, wafarin, or heparin (7 days before hospitalization)

Design outcomes

Primary

MeasureTime frame
The score calculated from the GOS benchmark in relation to the patient's life condition. Timepoint: Daily until 3 months later. Method of measurement: GOS criteria.;The score calculated from the DRS measurement criterion in relation to the patient's state of consciousness and function. Timepoint: Daily until 3 months later. Method of measurement: DRS criteria.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEsmaeil Alipour

Ahvaz University of Medical Sciences

Dr.alipour37@gmail.com+98 61 3373 8383

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026