Female infertility. Female infertility, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Sildenafil and estradiol, made in Iran and Marham Daroo Company, a vaginal tablet of sildenafil 25 mg and an oral tablet of estradiol 2 mg every 12 hours are prescr
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
No minimum to 40 Years
Inclusion criteria
Inclusion criteria: The number of sperm in female spouses is between 5-10 million. Sperm motility of female spouses should be between 25-30%. The normal morphology of female spouses sperm is between 3-4%. Women's body mass index should be less than 40. Endometrial thickness less than 7 mm.
Exclusion criteria
Exclusion criteria: Hypotension History of endocrine diseases History of stroke or heart attack Cardiovascular problems Consumption of nitrites or nitrates
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial thickness. Timepoint: Measurement of endometrial thickness at the beginning of the study (before the start of the intervention, which should be less than 7 mm) and 14 days after the start of taking an oral estradiol tablet and a sildenafil vaginal tablet. Method of measurement: Ultrasound device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNiloofar Mehry
Kashan University of Medical Sciences
Outcome results
None listed