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The effect of ketamine and oxytocin on pain control, nausea, blood pressure, heart rate, satisfaction, postoperative blood oxygen saturation in patients undergoing elective laparoscopic gallbladder surgery

The effect of ketamine and oxytocin on postoperative pain control in patients undergoing elective laparoscopic gallbladder surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210108049969N1
Enrollment
120
Registered
2021-01-10
Start date
2019-12-14
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Status and comparison of pain after laparoscopic cholecystectomy in 3 study group. Condition 2: Status and comparison of nausea after laparoscopic cholecystectomy in 3 study group. Condition 3: Status and comparison of hemodynamic changes (blood pressure, heart rate, blood oxygenation) after laparoscopic cholecystectomy in 3 study group.

Interventions

Intervention 1: Intervention group: Receiving 0.5 mg of ketamine per kg of patient weight and oxytocin 0.5 units per kg of patient weight immediately after patient extubation. All of the following wer

Sponsors

Khoram-Abad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged 30-60 years who have undergone laparoscopic cholecystectomy No pulmonary disease ASA class 1(American Society of Anesthesiologists ) is a system for assessing the fitness of patients before surgery No history of chronic pain after surgery

Exclusion criteria

Exclusion criteria: History of chronic pain Specific drug dependence such as opium History of psychiatric illness

Design outcomes

Primary

MeasureTime frame
Pain score based on visual analague scale. Timepoint: After surgery in the recovery room, 1 and 2 hours after surgery. Method of measurement: Visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Baghizadeh Baghdashti

Khoram-Abad University of Medical Sciences

M.baghizadeh65@gmail.com+98 66 3323 6401

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026