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The effect of adding different doses of neostigmine in peribulbar block for cataract surgery

The effect of adding different doses of neostigmine in peribulbar block for intraoperative anesthesia and post-operative analgesia in cataract surgery

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210106049952N1
Enrollment
60
Registered
2021-01-10
Start date
2021-01-15
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peribulbar block in adult patients undergoing cataract surgery..

Interventions

Intervention 1: Control group (Group C): Includes 20 patients. Each will receive 9 ml of lidocaine 2% (containing 1 ml = 10 unit of hyaluronidase) + 1 ml of saline. Intervention 2: Intervention group

Sponsors

Research Institute of Ophthalmology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Cataract surgery patients (male or female) aged from 30 to 70 years ASA physical status I, II, or III

Exclusion criteria

Exclusion criteria: Coagulopathy or use of anticoagulant drugs Infection at the site of surgery Posterior staphyloma Previous allergy or adverse reaction to the used drugs Bronchial asthma or bradyarrhythmia

Design outcomes

Primary

MeasureTime frame
Hemodynamics (heart rate, blood pressure, and oxygen saturation). Timepoint: Baseline, immediately after the block, and one hour after the block. Method of measurement: Electronic vital signs monitor.;Onset of sensory block. Timepoint: Every 5 seconds after the block. Method of measurement: Clinical assessment.;Onset of motor block. Timepoint: Every 5 seconds after the block. Method of measurement: Clinical assessment.

Secondary

MeasureTime frame
Duration of the block. Timepoint: Every 10 minutes following the block. Method of measurement: Clinical assessment.;Postoperative pain. Timepoint: Immediately after the block. Method of measurement: Visual analog scale.;Surgeon satisfaction. Timepoint: Immediately after the block. Method of measurement: Questioning.;Patient satisfaction. Timepoint: Immediately after the block. Method of measurement: Questioning.;First analgesic dose. Timepoint: Every 30 minutes. Method of measurement: Clinical assessment.

Countries

Egypt

Contacts

Public ContactDr. Iman Sobhy

Research Institute of Ophthalmology

iman.sobhy333@gmail.com+20 2 35718304

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 16, 2026