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Memantine and borderline personality disorder

The effect of memantine on the symptoms of Borderline personality disorder in the Iranian population

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210106049948N1
Enrollment
40
Registered
2021-02-21
Start date
2021-04-21
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Borderline personality disorder. Borderline personality disorder

Interventions

Intervention 1: The placebo group will receive a placebo for 12 weeks. At the end of weeks 2, 4, 6, and 8, BPD symptoms will be evaluated by the Best test. Blood samples will be gathered before the i

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women or men between the ages of 16 and 45 who have been diagnosed with BPD using the BEST tool for the disease.

Exclusion criteria

Exclusion criteria: Clinical evidence of any pathology in the central nervous system, neurological disorders, head injuries, epilepsy or history of seizures Pregnancy or breastfeeding Taking medications that may interact with memantine

Design outcomes

Primary

MeasureTime frame
Serum levels of memantine. Timepoint: Measurement of serum levels of memantine at the beginning of the study (before the intervention) and at the end of the treatment period. Method of measurement: High Performance Liquid Chromatograpy.;Symptoms. Timepoint: beginning of the study (before the intervention) and At the end of weeks 2, 4, 6 and 8. Method of measurement: The Best test.

Secondary

MeasureTime frame
Number of suicides. Timepoint: At the beginning of the study (before the intervention) and at the end of the intervention. Method of measurement: interview with patients.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFariba Karimzadeh

Iran University of Medical Sciences

fariba_karimzadeh@yahoo.com+98 21 8670 4725

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026