Comparison of the effect of 12 weeks of aerobic and combined training based on performance indicators and some other cardiovascular risk factors affected by amputation

The Comparison of Eeffect of Aerobic and Combined Exercise Training on Functional Indicators and some cardiovascular risk factors in lower-limb amputee

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210104049939N1

Enrollment

Registered

2023-06-01

Start date

2023-03-21

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower limb amputation veterans.

Interventions

Intervention 1: Intervention group: Aerobic exercise: Aerobic group exercises include 12 weeks of exercises, 3 sessions per week and each session is between 30 and 50 minutes and with increasing load.

Eligibility

Sex/Gender

Male

Age

45 Years to 60 Years

Inclusion criteria

Inclusion criteria: Lower extremity amputation veteran Written consent to enter the research Do not have a history of regular sports activities Have no history of advanced metabolic disease Do not smoke Age 45 to 60 years old Being male

Exclusion criteria

Exclusion criteria: Veterans of upper limb amputation and spinal cord amputation Having a regular sports record Having advanced metabolic disease smoking Infectious diseases such as influenza and covid Failure to participate in training

Design outcomes

Primary

Measure	Time frame
Improvement of C-reactive protein level in the blood of lower limb amputees due to exercise.due to exercise. Timepoint: 24 hours before the start of the study and 24 hours after 12 weeks of aerobic and combined training at rest and after 10 hours of overnight fasting, the initial blood sample of 10 cc will be taken from the frontal vein of the subjects. Method of measurement: Blood tests.;Improving the level of interleukin-6 in the blood of lower limb amputees due to aerobic and combined exercise. Timepoint: 24 hours before the start of the study and 24 hours after 12 weeks of aerobic and combined training at rest and after 10 hours of overnight fasting, the initial blood sample of 10 cc will be taken from the frontal vein of the subjects. Method of measurement: Blood tests.;Improving the level of v-cam in the blood of lower limb amputees due to aerobic and combined exercise. Timepoint: 24 hours before the start of the study and 24 hours after 12 weeks of aerobic and combined training at rest and after 10 hours of overnight fasting, the initial blood sample of 10 cc will be taken from the frontal vein of the subjects. Method of measurement: Blood tests.;Improving blood ESR levels of lower limb amputees due to aerobic and combined exercise. Timepoint: 24 hours before the start of the study and 24 hours after 12 weeks of aerobic and combined training at rest and after 10 hours of overnight fasting, the initial blood sample of 10 cc will be taken from the frontal vein of the subjects. Method of measurement: Blood tests.;Improving the fasting blood sugar level of lower limb amputees due to aerobic and combined exercise. Timepoint: 24 hours before the start of the study and 24 hours after 12 weeks of aerobic and combined training at rest and after 10 hours of overnight fasting, the initial blood sample of 10 cc will be taken from the frontal vein of the subjects. Method of measurement: Blood tests.;Improvement of systolic blood pressure of lower limb amputees due to aero	—

Measure

Time frame

Improvement of C-reactive protein level in the blood of lower limb amputees due to exercise.due to exercise. Timepoint: 24 hours before the start of the study and 24 hours after 12 weeks of aerobic and combined training at rest and after 10 hours of overnight fasting, the initial blood sample of 10 cc will be taken from the frontal vein of the subjects. Method of measurement: Blood tests.;Improving the level of interleukin-6 in the blood of lower limb amputees due to aerobic and combined exercise. Timepoint: 24 hours before the start of the study and 24 hours after 12 weeks of aerobic and combined training at rest and after 10 hours of overnight fasting, the initial blood sample of 10 cc will be taken from the frontal vein of the subjects. Method of measurement: Blood tests.;Improving the level of v-cam in the blood of lower limb amputees due to aerobic and combined exercise. Timepoint: 24 hours before the start of the study and 24 hours after 12 weeks of aerobic and combined training at rest and after 10 hours of overnight fasting, the initial blood sample of 10 cc will be taken from the frontal vein of the subjects. Method of measurement: Blood tests.;Improving blood ESR levels of lower limb amputees due to aerobic and combined exercise. Timepoint: 24 hours before the start of the study and 24 hours after 12 weeks of aerobic and combined training at rest and after 10 hours of overnight fasting, the initial blood sample of 10 cc will be taken from the frontal vein of the subjects. Method of measurement: Blood tests.;Improving the fasting blood sugar level of lower limb amputees due to aerobic and combined exercise. Timepoint: 24 hours before the start of the study and 24 hours after 12 weeks of aerobic and combined training at rest and after 10 hours of overnight fasting, the initial blood sample of 10 cc will be taken from the frontal vein of the subjects. Method of measurement: Blood tests.;Improvement of systolic blood pressure of lower limb amputees due to aero

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaliheh Heydari

Najafabad Azad University

info @ iaun.ac.ir+98 31 4229 2929

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026