Comparison of the effects of different probiotics

Comparison of the effect of probiotic drops pedilact and reuteflor in reducing prematurity complications in premature neonates

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210102049922N1

Enrollment

Registered

2021-06-11

Start date

2021-06-15

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Necrotizing enterocolitis. Condition 2: Neonatal jaundice. Necrotizing enterocolitis of newborn Neonatal jaundice associated with preterm delivery

Interventions

Intervention 1: The first intervention group includes neonates who will receive 5 drops of probiotic Pedilact drops made by Iran Zist takhmir Company, daily with breast milk or formula for 7 days. Int

Eligibility

Sex/Gender

All

Age

No minimum to 7 Days

Inclusion criteria

Inclusion criteria: Premature neonates (gestational age less than 37 weeks) aged from birth to 7 days of age were admitted at the time of feeding with a weight of 1000 to 2000 gr.

Exclusion criteria

Exclusion criteria: Severe asphyxia Intracerebral hemorrhage( ICH) Major congenital anomaly Early neonatal sepsis

Design outcomes

Primary

Measure	Time frame
Duration of hospitalization. Timepoint: Daily. Method of measurement: Calendar.;Time to full enteral feeding. Timepoint: Daily. Method of measurement: Calendar.;Duration of oxygen therapy. Timepoint: Daily. Method of measurement: Calendar.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRezaei Rana

Birjand University of Medical Sciences

rezaeir9@mums.ac.ir+98 56 3162 2001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026