Effect of remifentale and a combination of apotel and Pethidine in reducing labor pain

Comparison of analgesic effect of remifentanil versus combination of apotel and pethidine on labor pain among mothers candidate for normal vaginal delivery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210101049907N1

Enrollment

100

Registered

2021-01-30

Start date

2021-03-10

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor pain. Encounter for full-term uncomplicated delivery

Interventions

Intervention 1: Intervention group: Intravenous Remifentanil 0.05 µg/kg/min (Tofigh Daru Co.) and intravenous injection of placebo (6.7 ml) and 1 ml intramuscular injection of placebo. Intervention 2:

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Over 37 weeks pregnancy First or second pregnancy Singleton

Exclusion criteria

Exclusion criteria: Malpresentation of fetus Macrosomia

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Before analgesic administrations and two times (30 and 60 min) after intervention. Method of measurement: Visual analog scale.	—

Secondary

Measure	Time frame
Apgar. Timepoint: 1 and 5 minutes after birth. Method of measurement: Apgar test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZohre Roshani

Ardabil University of Medical Sciences

z.roshani@arums.ac.ir+98 45 3324 8888

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026