Evaluation of the effect of Horse Chestnut seed extract spray on sleep apnea

Evaluation of the effect of Horse Chestnut seed extract spray on improving and reducing the symptoms of sleep apnea

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201228049868N3

Enrollment

Registered

2022-09-05

Start date

2022-09-11

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep apnea. Sleep apnea

Interventions

Intervention group: Inhalation of one puff of Horse Chestnut seed extract spray every 8 hours inside each nostril for 14 days (Preparation of extract in Faculty of Pharmacy of Birjand).

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Sleep disorder Nocturnal snoring Daily fatigue Uncontrolled blood pressure Pittsburgh Sleep Quality Index=6

Exclusion criteria

Exclusion criteria: Patients with a history of liver and kidney disease Pregnant and lactating women Children under 18 years old Anticoagulant consumption and continuous use of aspirin Having a cardiac pacemaker History of allergy to any chemical, herbal, or medicinal compound Patients with a history of taking various narcotic and psychoactive drugs

Design outcomes

Primary

Measure	Time frame
Pittsburgh Sleep Quality Index. Timepoint: Before the intervention and 14 days after the intervention. Method of measurement: Pittsburgh Sleep Quality Index.	—

Secondary

Measure	Time frame
Adverse effects. Timepoint: 14 days after the intervention. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Mohammad Mousavi Mirzaei

Birjand University of Medical Sciences

mousavim903@bums.ac.ir+98 56 3162 6000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026