Effects of Platelet-rich-fibrin on Post-surgical Complications of Impacted wisdom tooth surgery

Effects of Platelet-rich fibrin (PRF) on Post-surgical Complications of Impacted wisdom tooth surgery in adults

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201227049849N1

Enrollment

Registered

2021-01-13

Start date

2021-01-09

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Platelet-rich fibrin.

Interventions

Intervention 1: Intervention group: Placement of Platelet-rich fibrin taken from patient's blood sample in empty extracted tooth socket and suturing the flap with 3/0 silk cord. Intervention 2: Contr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adults Patients with bilateral inter-bone impacted wisdom tooth

Exclusion criteria

Exclusion criteria: Pregnancy Lactation Having pre-operative sign or symptom Existence of pathology in impaction area Allergy to Penicillin, Paracetamol, chlorhexidine

Design outcomes

Primary

Measure	Time frame
Post-operative pain degree. Timepoint: First 7 days after surgery. Method of measurement: 0-10 Numeric Pain Rating Scale.;Post-operative edema amount. Timepoint: 1,3 and 7 days after surgery. Method of measurement: The distance between tragus and mouth commissure in horizontal plane and the distance between lateral cantus and gonion in vertical plane, would be measured by a flexible band.;Post-operative bleeding amount. Timepoint: 3 and 7 days after surgery. Method of measurement: Massive, uncontrollable bleeding since 2nd day of surgery would be conformed by patient.;Post-operative infection manifestation. Timepoint: 4- 7 days after surgery. Method of measurement: Assessment of pus discharge, redness and temperature increasing after the 3rd day after surgery.;Post-operative dry socket manifestation. Timepoint: 4- 7 days after surgery. Method of measurement: Presence of extreme pain not being decreased by taking analgesics and empty socket without pus discharge or fever.	—

Measure

Time frame

Post-operative pain degree. Timepoint: First 7 days after surgery. Method of measurement: 0-10 Numeric Pain Rating Scale.;Post-operative edema amount. Timepoint: 1,3 and 7 days after surgery. Method of measurement: The distance between tragus and mouth commissure in horizontal plane and the distance between lateral cantus and gonion in vertical plane, would be measured by a flexible band.;Post-operative bleeding amount. Timepoint: 3 and 7 days after surgery. Method of measurement: Massive, uncontrollable bleeding since 2nd day of surgery would be conformed by patient.;Post-operative infection manifestation. Timepoint: 4- 7 days after surgery. Method of measurement: Assessment of pus discharge, redness and temperature increasing after the 3rd day after surgery.;Post-operative dry socket manifestation. Timepoint: 4- 7 days after surgery. Method of measurement: Presence of extreme pain not being decreased by taking analgesics and empty socket without pus discharge or fever.

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Countries

Iran (Islamic Republic of)

Contacts

Public Contact????????? ?????????

Kashan University of Medical Sciences

kiani-p@kaums.ac.ir+98 31 5554 0021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026