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Evaluation of treatment of constipation induced infection

Evaluation of treatment of constipation-induced infection in patients with grade IIb, III skin burn

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201226049834N1
Enrollment
120
Registered
2021-05-01
Start date
2021-05-05
Completion date
Unknown
Last updated
2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Constipation. Constipation

Interventions

Intervention 1: Intervention group: Patients in this group will be treated for symptomatic constipation according to the guideline. The procedure is as follows: One adult Bisacodyl tablet (40 mg) is g

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Grade IIb, III upper-lower limb burns Burn percentage between 20 to 30

Exclusion criteria

Exclusion criteria: History of neurological diseases including dementia, Alzheimer's, Parkinson's History of psychologic illnesses including known and treated depression and anxiety, mania and schizophrenia Any allergies to laxatives or enzymes used History of Inflammatory bowel disease and Irritable bowel syndrome Coma or loss of consciousness Moderate to severe water and electrolyte disturbance Simultaneous presence of other traumas other than burns Perineal or anal burns History of diabetes, hypertension, heart, respiratory, liver and kidney

Design outcomes

Primary

MeasureTime frame
Evaluation of patients' constipation status. Timepoint: Maximum three days and examination every 12 hours from the beginning of the interventions. Method of measurement: Examination and clinical questions.;Wound infection caused by constipation. Timepoint: Duration of hospitalization of patients in infectious wards and intensive care. Method of measurement: Clinical examination and laboratory results.

Secondary

MeasureTime frame
Incidence of burn wound infection. Timepoint: Duration of hospitalization of patients in infectious wards and intensive care. Method of measurement: Clinical examination and laboratory results.;Incidence of constipation. Timepoint: Duration of hospitalization of patients in infectious wards and intensive care. Method of measurement: Patient records and clinical examinations.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAliakbar Jafarian

Iran University of Medical Sciences

Jafarian.ak@iums.ac.ir+98 21 8877 0031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026