LUTS In patients with benign prostatic hyperplasia. Personal history of diseases of genitourinary system
Conditions
Interventions
Intervention 1: Disport Botox injection of 300 mg diluted with 10 cc of normal saline is injected into the bladder detrusor once after transurethral resection of the prostate. Intervention 2: Control
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
45 Years to 84 Years
Inclusion criteria
Inclusion criteria: Obstructive symptoms of urinary obstruction defined by IPSS and enlarged prostate on DRE examination Consent to enter the study Existence of LUTS symptoms OAB and DO approval with biodynamics and Eurodynamics study
Exclusion criteria
Exclusion criteria: Patients with neurological diseases such as Parkinson's or stroke Prostate or bladder cancer People who have had bladder or prostate surgery in the past Dissatisfaction with enrollment Allergy to sulifenacin or Botox
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IPSS(International Prostate Score System) in two groups of botulinum and sulifenacin injection after TURP(Trans Urethral Resection Of Prostate) at 1, 3 and 6 months after treatment. Timepoint: 1, 3 and 6 months after transurethral resection of the prostate are checked. Method of measurement: Based on the International Index of Prostate Symptoms.;Urgent incontinence in the two groups of botulinum and sulifenacin injections after TURP(International Prostate Score System) is performed at 1, 3 and 6 months after treatment. Timepoint: 1, 3 and 6 months after transurethral resection of the prostate are checked. Method of measurement: It is done based on the patient's question.;Prostate volume in the two treatment groups of botulinum and sulifenacin injection after TURP(International Prostate Score System) is done at 1, 3 and 6 months after treatment. Timepoint: 1, 3 and 6 months after transurethral resection of the prostate are checked. Method of measurement: It is done based on ultrasound.;PVR(Post Voiding Residue) is performed in two treatment groups botulinum and sulifenacin injection after TURP(International Prostate Score System) at 1, 3 and 6 months after treatment. Timepoint: 1, 3 and 6 months after transurethral resection of the prostate are checked. Method of measurement: Based on Urodynamic test.;Q MAX(Q maximum) is administered in two treatment groups botulinum and sulifenacin injection after TURP(International Prostate Score System) at 1, 3 and 6 months after treatment. Timepoint: 1, 3 and 6 months after transurethral resection of the prostate are checked. Method of measurement: Based on Urodynamic test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Farzad Allame
Shahid Beheshti University of Medical Sciences
Outcome results
None listed