Impact of platelet-rich plasma on anal fissure

Evaluating the effect of autologous platelet-rich plasma on the improvement of therapeutic effectiveness of the classic approach to anal

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201225049826N1

Enrollment

Registered

2021-12-01

Start date

2021-06-22

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

??Anal fissure. Fissure and fistula of anal and rectal regions

Interventions

Intervention 1: Intervention group: A group of patients with anal fissures who, in addition to the classic treatment, receive PRP as an injection at the base of the wound. In order to prepare PRP or p

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients diagnosed with anal fissure Consent for entering to the study

Exclusion criteria

Exclusion criteria: Patients with inflammatory bowel disease or other conditions which can cause secondary anal fissure Patients with diabetes Patients with immune deficiency

Design outcomes

Primary

Measure	Time frame
Incidence of wound healing. Timepoint: Initiation of the study, two weeks after injection, four weeks after injection, one month after the first injection. Method of measurement: Depending on the amount of pain, bleeding during defecation, itching and the appearance of the wound from the surgeon's point of view.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Ebrahimibagha

Shahid Beheshti University of Medical Sciences

h.ebrahimi@sbmu.ac.ir+98 21 2243 9770

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026