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Evaluation of the effect of Lactobacillus ruteri in the treatment of Helicobacter pylori with clarithromycin, pantoprazole and amoxicillin regimen

Assessment effect of Lactobacillus Reuteri (pyloshot) in H.pylori eradication with clarithromycin, amoxicillin and pantoprazole

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201225049825N1
Enrollment
76
Registered
2021-02-12
Start date
2021-01-20
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection.

Interventions

Intervention 1: Intervention group: In this group, in addition to the standard and routine treatment , which includes two antibiotics (amoxicillin one gram twice a day and clarithromycin five hundred

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: Have Helicobacter pylori The patient volunteering to participate in the study, Age 40-75 years Be a resident of Arak.

Exclusion criteria

Exclusion criteria: Having a metastatic cancer Pregnancy Breastfeeding History of failure of previous H.PYLORI treatment Incomplete prescribed treatment regimen Irregular use of medications and non-adherence to the prescribed treatment regimen Previous gastrectomy Suffering from incurable diseases Patients with IHD Chronic renal failure GI bleeding Malignancy Concomitant use of tetracycline, quinolone, bisphosphonates, and levothyroxine (drug interaction) People undergoing chemotherapy Short Bowel Syndrome Anemia and neutropenia fever History of drug and food allergies Hypercalcemia

Design outcomes

Primary

MeasureTime frame
Helicobacter pylori infection using fecal antigen test. Timepoint: At the beginning of the study and 4 weeks after the intervention. Method of measurement: Stool antigen test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Hashemi

Arak University of Medical Sciences

Drhashemiz2018@gmail.com+98 86 3368 3717

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026