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Investigation of the effect of Krocina on decreasing Addict Withdrawal Syndrome, Craving , Depression and Stress

The effect of Krocina on decreasing Addict Withdrawal Syndrome, Craving , Depression and Stress: A double blind randomized parallel clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201223049818N1
Enrollment
72
Registered
2021-01-12
Start date
2021-01-10
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid dependence with withdrawal symptoms. Opioid dependence with withdrawal

Interventions

Intervention 1: Intervention group: Patients will take two tablets daily containing 15 mg of Krocina powder made by the pharmacist in the morning and evening for six weeks. Intervention 2: Control gro

Sponsors

Shahroud University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Age 18 to 64 years Male phenotype Not having a mood disorder in the past Finish of outpatient detoxification Having a negative urine test absence of simultaneous presence in another study

Exclusion criteria

Exclusion criteria: Acute psychiatric illness at the time of drug initiation The patient develops symptoms of psychosis and is unable to continue cooperating consciously and satisfactorily with the plan.

Design outcomes

Primary

MeasureTime frame
Craving: The tendency to re-use the substance. Timepoint: At the beginning of the study and 7, 14, 21, 28, 35 and 42 days after the start of the intervention. Method of measurement: OCDUS questionnaire.

Secondary

MeasureTime frame
Persistence on treatment: The success rate of a person dependent on opioid use on not using opioid after the detoxification period. Timepoint: At the beginning of the study and 7, 14, 21, 28, 35 and 42 days after the start of the intervention. Method of measurement: Urine Rapid Test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Jomehpour

Shahroud University of Medical Sciences

hjomehpour@yahoo.com+98 51 3881 2081

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026