A comparison of the effect of Nasal Continuous Positive Airway Pressure (NCPAP) vs Nasal high-frequency oscillation(NHFO) in the treatment of respiratory distress in preterm infants

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201222049795N1

Enrollment

Registered

2021-01-09

Start date

2020-09-30

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal respiratory distress syndrome. Respiratory distress syndrome of newborn

Interventions

Intervention 1: First intervention group: Nasal Continuous Positive Airway Pressure group

These infants underwent non-invasive ventilation Continuous Positive Airway Pressure using Bi nasal prong, Bubble Continuous Positive Airway Pressure, hot and humid airflow, and blender. Continuous Po

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Gestational age between 25 to 35 weeks Moderate to severe respiratory distress syndrome

Exclusion criteria

Exclusion criteria: Patients with congenital anomalies Patients needed endotracheal intubation

Design outcomes

Primary

Measure	Time frame
Preterm infants. Timepoint: Determining premature infants at the beginning of the study. Method of measurement: By measuring gestational age between 25 to 35 weeks.;Respiratory distress. Timepoint: At the beginning of the study. Method of measurement: Using medical examinations.	—

Secondary

Measure	Time frame
O2 Therapy. Timepoint: at any time interval of study If it's needed. Method of measurement: Using medical examinations.;O2 Therapy time. Timepoint: While O2 Therapy. Method of measurement: Counting the days of oxygen therapy.;Invasive mechanical ventilation. Timepoint: at any time interval of study If it's needed. Method of measurement: If the infant does not respond to non-invasive mechanical ventilation.;Duration of using mechanical ventilation. Timepoint: While using mechanical ventilation. Method of measurement: Counting the days of using mechanical ventilation and Using the data collection form.;The infant's age at the time of use of mechanical ventilation. Timepoint: While using mechanical ventilation. Method of measurement: Age is calculated based on hours and Using the data collection form.;Apnea. Timepoint: At any time of apnea During or after being placed under the studied devices. Method of measurement: By observing the infant's breathing measuring devices.;The infant's age at the time of apnea. Timepoint: At any time of apnea. Method of measurement: Age is calculated based on hours and Using the data collection form.;Surfactant. Timepoint: At any time of study if necessary. Method of measurement: Based on the physician's opinion and when there is no progress in the infant's respiratory recovery.;Age of infants at surfactant indication. Timepoint: At the time of surfactant indication. Method of measurement: Age is calculated based on hours and Using the data collection form.;Pneumothorax. Timepoint: During or after being placed under the studied devices. Method of measurement: By imaging and examination.;Age of infant's at the pneumothorax incidence. Timepoint: At the time of pneumothorax incidence. Method of measurement: Age is calculated based on hours and Using the data collection form.;IVH (Intra ventricular hemorrhage). Timepoint: During or after being placed under the studied devices. Method of measurement: imaging.;Age of infant's at intraventricul	—

Measure

Time frame

O2 Therapy. Timepoint: at any time interval of study If it's needed. Method of measurement: Using medical examinations.;O2 Therapy time. Timepoint: While O2 Therapy. Method of measurement: Counting the days of oxygen therapy.;Invasive mechanical ventilation. Timepoint: at any time interval of study If it's needed. Method of measurement: If the infant does not respond to non-invasive mechanical ventilation.;Duration of using mechanical ventilation. Timepoint: While using mechanical ventilation. Method of measurement: Counting the days of using mechanical ventilation and Using the data collection form.;The infant's age at the time of use of mechanical ventilation. Timepoint: While using mechanical ventilation. Method of measurement: Age is calculated based on hours and Using the data collection form.;Apnea. Timepoint: At any time of apnea During or after being placed under the studied devices. Method of measurement: By observing the infant's breathing measuring devices.;The infant's age at the time of apnea. Timepoint: At any time of apnea. Method of measurement: Age is calculated based on hours and Using the data collection form.;Surfactant. Timepoint: At any time of study if necessary. Method of measurement: Based on the physician's opinion and when there is no progress in the infant's respiratory recovery.;Age of infants at surfactant indication. Timepoint: At the time of surfactant indication. Method of measurement: Age is calculated based on hours and Using the data collection form.;Pneumothorax. Timepoint: During or after being placed under the studied devices. Method of measurement: By imaging and examination.;Age of infant's at the pneumothorax incidence. Timepoint: At the time of pneumothorax incidence. Method of measurement: Age is calculated based on hours and Using the data collection form.;IVH (Intra ventricular hemorrhage). Timepoint: During or after being placed under the studied devices. Method of measurement: imaging.;Age of infant's at intraventricul

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Jandaghi

Islamic Azad University

M.Jandaghi73@gmail.com+98 23 3332 3194

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026