Efficacy of Photodynamic therapy with topical Indocyanine green in the treatment of Keloidal lesions

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201221049780N1

Enrollment

Registered

2021-03-17

Start date

2021-04-21

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

keloid. Hypertrophic scar

Interventions

Intervention group: patients under treatment with indocyanine green 0.2% ointment and photodynamic therapy after 1 hour, every 2 weeks for total of 6 sessions.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: the patients are selected based on dermatologist diagnosis as having idiopathic keloids minimum age for being selected is 18 years old patients have no history of any medical treatments for their lesions at least in 3 months lesions are on trunk, extremities, back and buttock

Exclusion criteria

Exclusion criteria: any skin disease or abnormality around the lesion for example dermatitis, bacterial or fungal infections pregnancy lactation lesions on face and genitalia history of any medical treatments for their lesions in 3 last months

Design outcomes

Primary

Measure	Time frame
Improvement of keloidal lesions based on POSAS score. Timepoint: before the trial, every month after starting trial, in 6th and 12th weeks after finishing the trial. Method of measurement: Patient and Observer Scar Assessment Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Fakhraei

Mashhad University of Medical Sciences

fakhraeis971@mums.ac.ir+98 51 3802 2031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026