Condition 1: Malignant neoplasm of base of tongue. Condition 2: Malignant neoplasm of other and unspecified parts of tongue. Condition 3: Malignant neoplasm of oropharynx. Condition 4: Malignant neoplasm of nasopharynx. Condition 5: Malignant neoplasm of hypopharynx. Condition 6: Malignant neoplasm of pyriform sinus. Condition 7: Malignant neoplasm of larynx. Malignant neoplasm of base of tongue Malignant neoplasm of other and unspecified parts of tongue Malignant neoplasm of oropharynx Mali
Conditions
Interventions
Intervention 1: Intervention group:In this group, they received cisplatin every 21 days at a dose of 100 mg per cubic meter divided into three consecutive days. Chemotherapy courses were between 2 an
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Men and women under 70 years of age, known case of head and neck SCC with karnofsky performance status >= 70% Definitive chemoradiation or adjuvant chemoradiation in patients with extranodal extension or positive margin Radiation dose 66-70 Gy
Exclusion criteria
Exclusion criteria: History of chemotherapy Kidney disease and Diabetes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mucositis. Timepoint: Weekly during radiation for 7 weeks. Method of measurement: Examination.;Disphasia. Timepoint: Weekly during radiation for 7 weeks. Method of measurement: Examination.;Cytopenia. Timepoint: Weekly during radiation for 7 weeks. Method of measurement: Laboratory data. | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease free survival. Timepoint: 18 months. Method of measurement: Phone calls. Visit at the Office.;Overall survival. Timepoint: 18 months. Method of measurement: Phone calls. Visit at the Office. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArefeh Saeedian
Tehran University of Medical Sciences
Outcome results
None listed