Evaluation of the effects of Entonox and local anesthesia in painless delivery

Comparison of the effects of ENTONOX inhalation and regional anesthesia on labor pain reduction in vaginal delivery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201219049769N1

Enrollment

Registered

2021-01-03

Start date

2020-01-23

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Painless delivery.

Interventions

Intervention 1: Intervention group 1: Patients in this group were instructed to apply the Entonox mask firmly on the face and breathe in it as soon as uterine contractions begin, and continue to do so

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Single term pregnancy Cephalic presentation No problem in decending of fetus

Exclusion criteria

Exclusion criteria: Asthma Hypertension Diabetes Melitus Fetal distres and death Massive vaginal bleeding Placenta previa Infection in sight of injection Coagulopathy Severe headache Dyspnea

Design outcomes

Primary

Measure	Time frame
Analgesic rate based on Visual Analogue Scale. Timepoint: Group A once before inhalation of Entonox and once after 4 inhalations and group B before anesthesia and 5 minutes after anesthesia. Method of measurement: Visual Analogue Scale will be used to measure pain.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactYousf kolookhy

Islamic Azad University

najibfarokhi@gmail.com+98 23 3239 2661

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026