Smoking disorder in patients with schizophrenia. Nicotine dependence
Conditions
Interventions
Intervention 1: Intervention group: Patients in the intervention group will undergo repetitive transcranial magnetic stimulation (rTMS) treatment in ten sessions (two weeks, with five sessions per wee
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Confirmation of the diagnosis of schizophrenia based on DSM-5 and according to a clinical interview conducted by a faculty psychiatrist Confirmation of the diagnosis of smoking disorder based on DSM-5 and according to a clinical interview conducted by a faculty psychiatrist Do not take clozapine Age 18 to 60 years No dependence on alcohol and other substances except nicotine Lack of criteria for other substance use disorders in the last three months Absence of clinical contraindications on rTMS such as metal, shunt or implant in the brain, history of brain surgery, increased intracranial pressure, pregnancy or attempt to conceive, history of seizures in the person and the presence of a pacemaker
Exclusion criteria
Exclusion criteria: Receive ECT at the same time
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of cigarettes smoked. Timepoint: Before and immediately after the intervention and one month later. Method of measurement: Question from the patient.;Craving for nicotine. Timepoint: Before and immediately after the intervention. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of positive and negative symptoms of schizophrenia. Timepoint: Before and immediately after the intervention. Method of measurement: Positive and negative syndrome scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGolnaz Zare Mehrjardi
Iran University of Medical Sciences
Outcome results
None listed