Ketamin mouthwash for Mucositus treatment

Double blind Comparision study on safty ang efficacy of Ketamin mouthwash in children above 7 years old with chemotherapy induced Mucositis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201218049750N1

Enrollment

Registered

2020-12-23

Start date

2019-03-23

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chemotherapy induced oral Mucositis. Oral mucositis (ulcerative) due to antineoplastic therapy

Interventions

Intervention 1: Intervention group: 20 patients with mucositis geare 3 ir 4 who rinse ketamin mouthwash 20 mg/5cc. Intervention 2: Control group: 20 matients with mucositis grade 3 or 4 who rinsed nor

Eligibility

Sex/Gender

All

Age

7 Years to 14 Years

Inclusion criteria

Inclusion criteria: Children above 7 years old with high grade Mucositus

Exclusion criteria

Exclusion criteria: History of psychosis, History of seizure History of allergy to ketamin

Design outcomes

Primary

Measure	Time frame
Mucositis grading. Timepoint: 1 hour after mouthwash rinisg, After esch day of trial. Method of measurement: Mucositis grading by examination.;Pain severity. Timepoint: 1 hour after rinsing mouthwash. At the end of each day of trial. Method of measurement: Questionnaire.;Oral Tolerance. Timepoint: 1 hour after rinsing mouthwash. At the end of each day of trial. Method of measurement: Questinnaire.;Mouthwash Onset of effect. Timepoint: 1 hour after rinsing mouthwash, at the end of each day of trial. Method of measurement: Questionnaire.;Mouthwash Duration of effect. Timepoint: 1 hour after rinsing mouthwash, at the end of each day of trial. Method of measurement: Questionnaire.	—

Measure

Time frame

Mucositis grading. Timepoint: 1 hour after mouthwash rinisg, After esch day of trial. Method of measurement: Mucositis grading by examination.;Pain severity. Timepoint: 1 hour after rinsing mouthwash. At the end of each day of trial. Method of measurement: Questionnaire.;Oral Tolerance. Timepoint: 1 hour after rinsing mouthwash. At the end of each day of trial. Method of measurement: Questinnaire.;Mouthwash Onset of effect. Timepoint: 1 hour after rinsing mouthwash, at the end of each day of trial. Method of measurement: Questionnaire.;Mouthwash Duration of effect. Timepoint: 1 hour after rinsing mouthwash, at the end of each day of trial. Method of measurement: Questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaral Hejrati

Shahid Beheshti University of Medical Sciences

Maral.hejratie.mh@gmail.com22227021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026