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the best concentration of injected hypertonic dextrose in knee prolotherapy

Evaluation of the effect of different concentrations of dextrose in prolotherapy on relieving knee osteoarthritis pain

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201214049707N1
Enrollment
93
Registered
2021-04-19
Start date
2021-05-05
Completion date
Unknown
Last updated
2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: first group : 16 millilitres of Dextrose 15 % plus 4 millilitres of lidocaine 2 %, inject in four points in the anterior and four points in the posterior of knee.

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to No maximum

Inclusion criteria

Inclusion criteria: At least three of this six criteria Age more than 50 year's Morning stiffness less than 30 minutes Cripitation in knee moves Bone sensivity Bone enlarged No feeling of arther warming

Exclusion criteria

Exclusion criteria: Stroid drugs injection in the last two weeks Diabetes mellitus Candidate for knee surgery( degree's of four in stiffness ) History of dextrose injection in knees Knee infection in the last three months Knee inflammation Daily opium use History of inflammatory or infected arthritis Heridatory or traumatic injury in knee joint Vascular necrosis Body mass index more than 30

Design outcomes

Primary

MeasureTime frame
Severity of pain is the most important item that is affected on disability of patients with knee osteoarthritis and in this research through the WOMAC score evaluate before and after the procedure. Timepoint: Before intervention, one, three and six months after the first injection. Method of measurement: Via questionnaire that designed for this research plus WOMAC score questionnaire.

Secondary

MeasureTime frame
Severity of the pain is the most important item and the most affected on patient's disability that evaluates. Morning stiffness is a limiter cause that evaluates. Restriction for daily activities will evaluates. Timepoint: Before intervention, one, three and six months after the first injection. Method of measurement: Via WOMAC score questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeid Biglary

Sanandaj University of Medical Sciences

Saeid.Biglary@muk.ac.ir+98 87 3362 8194

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026