Chronic sinusitis. Chronic sinusitis
Conditions
Interventions
Intervention 1: Intervention group: Azithromycin, received 500 mg single-dose azithromycin (SANA MED pharmaceutical Co., Iran) daily for 4 weeks. Intervention 2: Intervention group: Clarithromycin , r
Sponsors
Technology and Research Vice-chancellery, Hormozgan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Diagnosis of chronic sinusitis based on the Rhinosinusitis Task Force (RTF) criteria Confirmation of chronic sinusitis by CT scan 18-65 years of age
Exclusion criteria
Exclusion criteria: Presence of polyp, mass, or severe nasal septal deviation (requiring surgery or obstructing the sinus ostia) upon endoscopic examination Antibiotic use within the past 3 months Any topical drug (drop or spray) within the past month Sinus or nasal surgery Hypersensitivity to macrolides Pregnancy or lactation Diabetes mellitus Hypertension Cardiovascular diseases Periodontal infection of the tooth roots adjacent to the maxillary sinus Systemic illnesses involving the sinuses including Wegener's granulomatosis, sarcoidosis, malignancies, lymphoma, cystic fibrosis, AIDS, primary ciliary dyskinesia CT scan findings of inhomogeneous densities indicating probable fungal infections, unilateral involvement of the maxillary sinuses, and presence of mucous retention cysts in the maxillary sinus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of imaging findings. Timepoint: At the end of 4 weeks of treatment. Method of measurement: LMS (Lund-Mackay Staging) score.;Improvement of sinusitis symptoms. Timepoint: At the end of 4 weeks of treatment. Method of measurement: Patient's history. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehdi Askar
Bandare-abbas University of Medical Sciences
Outcome results
None listed