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Investigating the effect of propofol, ketamine and ketofol on agitation after herniorrhaphy

Comparison of the effects of propofol, ketamine, and ketofol on controlling agitation in children after herniorrhaphy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201207049639N9
Enrollment
105
Registered
2023-06-12
Start date
2023-07-23
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Agitation after surgery. Restlessness and agitation

Interventions

Intervention 1: Intervention group: For patients in group one, after induction of general anesthesia with sevoflurane, propofol 0.5 mg/kg will be injected intravenously. Intervention 2: Intervention g

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 4 Years

Inclusion criteria

Inclusion criteria: Children undergoing herniorrhaphy under general anesthesia Aged between 2-4 years Patients with physical status classified as ASA II and ASA III according to the criteria of the American Anesthesia Association (ASA).

Exclusion criteria

Exclusion criteria: Mental retardation Neurological diseases Anomaly of the upper airway History of asthma or other lung diseases Pulmonary infections in the last 4 weeks

Design outcomes

Primary

MeasureTime frame
Agitation score. Timepoint: After extubation, the time to leave the operating room, recovery and 30 minutes after surgery. Method of measurement: Four-point scale for assessing of agitation.

Secondary

MeasureTime frame
Pain severity. Timepoint: Recovery, 30 minutes after surgery. Method of measurement: Consolability cry activity leg face (FLACC ).;Heart rate. Timepoint: Every 15 minutes to one hour, and at hours 6, 12, and 24 after surgery. Method of measurement: Pulse oximetry.;Vomiting. Timepoint: Within 24 hours after surgery. Method of measurement: Clinical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hadi Hooshyar

Oroumia University of Medical Sciences

hooshyar.h@umsu.ac.ir+98 44 3193 8293

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026