Effect of norepinephrine with phenylephrine in the prevention of hypotension undergoing spinal anesthesia

Comparison of norepinephrine with phenylephrine in the prevention and treatment of hypotension in cesarean section undergoing spinal anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201207049639N8

Enrollment

Registered

2022-03-31

Start date

2022-04-21

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension. Hypotension

Interventions

Intervention 1: Intervention group 1: In all patients, 10 mg (2 cc) of bupivacaine 0.5% (Produced by Caspian company)is injected intrathecally, and after the patient is in a supine position, systolic

Eligibility

Sex/Gender

Female

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Satisfaction to participate in the study Age between 20 to 45 years Lack of sensitivity to norepinephrine and phenylephrine

Exclusion criteria

Exclusion criteria: Having liver, kidney and heart disease Sensitivity to anesthetics

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure. Timepoint: Before intervention, 5, 10, 15, 20, 25 and 30 minutes after intervention. Method of measurement: Blood pressure monitor.;Diastolic blood pressure. Timepoint: Before intervention, 5, 10, 15, 20, 25 and 30 minutes after intervention. Method of measurement: Blood pressure monitor.	—

Secondary

Measure	Time frame
Nausea and vomiting. Timepoint: It is recorded up to 30 minutes after the intervention if observed. Method of measurement: Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hadi Hooshyar

Oroumia University of Medical Sciences

hooshyar.h@umsu.ac.ir+98 44 3198 8293

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026