Skip to content

Evaluation of the Phenylephrine effect on hypotension in cesarean section

Evaluation of the prophylactic infusion effect of Phenylephrine on hypotension in cesarean section under spinal anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201207049639N1
Enrollment
100
Registered
2020-12-20
Start date
2019-03-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension. Hypotension

Interventions

Intervention 1: Intervention group: patients in the intervention group received 100 micrograms per hour of Phenylephrine infusion. Intervention 2: Control group: patients in the control group received

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Pregnant women candidates for cesarean section under spinal anesthesia American Society of Anesthesiologists classification system I and II (ASA II and ASA II)

Exclusion criteria

Exclusion criteria: Patients with classical hypertension Gestational hypertension Patients with pulmonary and cardiovascular diseases Patients with cerebrovascular disease Fetal abnormality

Design outcomes

Primary

MeasureTime frame
Hypotension, which was considered as a decrease in systolic blood pressure by 80% of the baseline. Timepoint: Before the intervention and in 5, 15, 25, 35 and 45 minutes after the intervention. Method of measurement: Blood pressure monitoring device.

Secondary

MeasureTime frame
Hypertension was considered as an increase in systolic blood pressure above 120% of the baseline. Timepoint: Before the intervention and in 5, 15, 25, 35 and 45 minutes after the intervention. Method of measurement: Blood pressure monitoring device.;Nausea. Timepoint: Before the intervention and in 5, 15, 25, 35 and 45 minutes after the intervention. Method of measurement: Interview.;Vomiting. Timepoint: Before the intervention and in 5, 15, 25, 35 and 45 minutes after the intervention. Method of measurement: Interview.;Bradycardia (decrease in heart rate to less than 60 beats per minute). Timepoint: Before the intervention and in 5, 15, 25, 35 and 45 minutes after the intervention. Method of measurement: Heart rate monitoring device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hadi Hooshyar

Oroumia University of Medical Sciences

hooshyar.h@umsu.ac.ir+98 44 3198 8293

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026