To evaluate the effect of single dose prophylactic vancomycin before semi-permanent catheterization to prevent catheter related infection: Randomized Controlled Trial, Phase 2

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201206049617N1

Enrollment

Registered

2020-12-15

Start date

2020-03-20

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Catheter related infection. Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts, initial encounter

Interventions

Intervention 1: Intervention group: Patients with end-stage renal disease receive one gram of the vancomycin antibiotic by intravenous injection one hour before the implantation of a semi-permanent ca

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patient with ESRD Not using antibiotics before the study sterile conditions during catheter installation Lack of evidence of infection in other parts of the body Satisfaction to participate in the study

Exclusion criteria

Exclusion criteria: No end-stage renal disease or no need to install a catheter for dialysis

Design outcomes

Primary

Measure	Time frame
Incidence of catheter-dependent infection. Timepoint: 6 months. Method of measurement: Blood culture, Catheter lumen culture and signs of infection including fever and purulent discharge from the catheter site.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZohreh Zandbaf

Ahvaz University of Medical Sciences

farajzadeh_h@ajums.ac.ir+98 61 3374 3001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 11, 2026