wound healing and preventing hypertrophic scars and keloids formation. Hypertrophic scar
Conditions
Interventions
Intervention 1: Intervention group: First a patient's scar will be categorized into two similar groups (Left and side). A Part of the scar selected randomly will be treated with Losartan ointment. The
Sponsors
Artesh University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: The patient’s scar length should be more than 10 centimeter, or they should have several scars with total length of 10 centimeter. The patient’s age should be between 18 to 50 years old.
Exclusion criteria
Exclusion criteria: The patients who did not regularly consume ointments will be excluded. The patients who are pregnant, consume antihypertensive drugs, or have history of cancer, allergy and bleeding or discharge at scar site will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scare assessment, Vancouver Scar Scale (VSS) assesses 4 variables: vascularity, height/thickness, pliability, and pigmentation. The overall score is between 0 to 13. Timepoint: Three and six months after ointment administration. Method of measurement: The evaluators are doctors who will use VSS or Vancouver scar scale to rate the scar change. Vancouver Scar Scale (VSS) assesses 4 variables: vascularity, height/thickness, pliability, and pigmentation. The overall score is between 0 to 13. | — |
Secondary
| Measure | Time frame |
|---|---|
| Itching is an irritating sensation of the skin which will be measured by the Visual Analogue Scale. Timepoint: Three and six months after ointment administration. Method of measurement: The evaluators are doctors and will be measured by the Visual Analogue Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBehzad Khodai
Artesh University of Medical Sciences
Outcome results
None listed