Effect of gluten free diet on irritable bowel syndrome symptoms

Comparison of the effect of gluten free diet and regular diet on severity of clinical symptoms in patients with irritable bowel syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201204049599N1

Enrollment

Registered

2021-02-13

Start date

2020-01-21

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable Bowel Syndrome. Irritable bowel syndrome

Interventions

Intervention 1: Intervention group: Gluten free group. in this group necessary education about gluten free diet and foods that patients must avoid including wheat, barley and rye will be provided. At

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Having Irritable bowel syndrome (IBS) according to ROME-IV diagnostic criterion Having IBS Symptoms according to ROME-IV diagnostic criterion Having informed consent and ability of participation in study and adherence to gluten free diet Being at least 18 years old

Exclusion criteria

Exclusion criteria: Having inflammatory, infectious or organic gastrointestinal disease Having coeliac disease Having Cirrhosis Using corticosteroids, non steroidal anti-inflammatory drugs, or medications that are effective in gastrointestinal tract movement Having thyroid disease Pregnancy Psychiatric conditions and inability to give informed consent Being on gluten free diet before entering the study

Design outcomes

Primary

Measure	Time frame
Abdominal Distention or Flatulence. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Abdominal pain. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Constipation. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Diarrhea. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Nausea and or vomiting. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Disease effect on daily life. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Mental well being. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Fecal urgency. Timepoint: Before intervention and after 4 weeks. Method of measurement: According to patient history.;Incomplete defecation sense. Timepoint: Before intervention and after 4 weeks. Method of measurement: According to patient history.	—

Measure

Time frame

Abdominal Distention or Flatulence. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Abdominal pain. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Constipation. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Diarrhea. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Nausea and or vomiting. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Disease effect on daily life. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Mental well being. Timepoint: Before intervention and after 4 weeks. Method of measurement: Visual Analogue Scale (VAS).;Fecal urgency. Timepoint: Before intervention and after 4 weeks. Method of measurement: According to patient history.;Incomplete defecation sense. Timepoint: Before intervention and after 4 weeks. Method of measurement: According to patient history.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Pashaee

Oroumia University of Medical Sciences

pashaee.m@umsu.ac.ir+98 44 3346 9931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026