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Effects of Aloe Vera on mucositis

Evaluation and comparison of the effects of Aloe vera on prevention and treatment of radiotherapy induced mucositis- Isfahan 2021

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201203049585N1
Enrollment
80
Registered
2021-02-11
Start date
2021-02-23
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck cancers. Oral mucositis (ulcerative) due to radiation

Interventions

Intervention 1: Intervention group: from the beginning of radiotherapy to the end of treatment, which lasts for an average of 6 weeks for each patient, patients are advised to gargle 5 cc of the recei

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Indication of Head and Neck radiotherapy Lack of previous history of radiation Lack of any mucusitis due to radiation or any other couses Lack of evidence of distant metastasis Karnofsky Performance Status at least 70 Not to use of NSAID or Steroids or other analgesics Absence of pregnancy At least 50 gray of radiation dose

Exclusion criteria

Exclusion criteria: Patient request to exit Patient die due to another reason Severe adverse effects

Design outcomes

Primary

MeasureTime frame
RTOG grading of mucusitis. Timepoint: Record of RTOG grade before and every week of treatment and end of radiation. Method of measurement: RTOG grading questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoya Mobini

Esfahan University of Medical Sciences

Roya.mobini@gmail.com+98 31 3775 2366

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026