The effect of morphine and oxycodone on bone metastatic pain

Comparison of the effect of morphine and oxycodone in relieving pain in patients with bone metastasis pain

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201202049575N1

Enrollment

Registered

2020-12-09

Start date

2020-12-21

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone metastasis. Malignant neoplasm of bone and articular cartilage of other and unspecified sites

Interventions

Intervention 1: First intervention group: In the first group, 16 patients received morphine sulfate (Darupakhsh-Iran) 5 mg intravenously once at the beginning of the intervention and two placebo table

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: All patients with malignancy whose bone metastasis has been confirmed by bone scan and are candidates for analgesia. Pain intensity less than 6 based on vas ruler

Exclusion criteria

Exclusion criteria: Have low blood pressure, Bradypnea Have a bone fractures History of diabetes and kidney failure

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Before the intervention, 30 minutes, 2 hours and 6 hours after the intervention. Method of measurement: visual analogue scale for pain.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdi Farahani

Arak University of Medical Sciences

research@arakmu.ac.ir+98 86 3417 3639

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026