Xerostomia. Disturbances of salivary secretion
Conditions
Interventions
Intervention 1: Intervention group: In this study, 60 gums containing ginger formulated by a pharmacist, weighing 1.5 g containing 0.15 g of ginger, are given to the intervention group. The duration o
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: People of both sexes over 18 years old Confirmation of dry mouth, regardless of the cause, by the standard dry mouth questionnaire, which includes questions related to the amount of saliva in the mouth, swallowing difficulty, a feeling of dryness while eating, the need to drink water while eating, will be examined.
Exclusion criteria
Exclusion criteria: Patients who are unable to chew gum due to oral conditions History of allergic reaction to chewing gum and its contents , including ginger Severe cognitive deterioration Effective conditions on salivary flow rate : salivary gland aplasia , severe dehydration , chemotherapy , radiation to the head and neck and medications includes : ( Tricyclics Anti Deppressants - Tranquiliser - Sedative - Anticoagulants - Antihistamines - Antihypertensive drugs - Antispasmodic and diuretics ) - Sjogren's syndrome - Diabetes Mellitus - Sarcoidosis - Human immuno deficiency virus - Hepatitis C - Graft versus Host Disease (GvHD) - Mental Disorders - Primary biliary Cirrhosis - Systemic lupus erythematosus - Rheumatoid arthritis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stimulated saliva level. Timepoint: Measurement of stimulated saliva and non-stimulating saliva before the intervention and 14 days after chewing gum. Method of measurement: Measurement of stimulated saliva in milliliters in a plastic vial. | — |
Secondary
| Measure | Time frame |
|---|---|
| Unstimulated saliva. Timepoint: Measurement of non-stimulating saliva before the intervention and 14 days after begining the intervention. Method of measurement: Measurement of non-stimulating saliva in milliliters in a plastic vial.;Oral health related quality of life. Timepoint: Before the intervention and 14 days after the intervention. Method of measurement: Oral Health Impact Profile-14 ( OHIP-Per14 ) questionnaire.;Severity of dry mouth. Timepoint: Before the intervention and 14 days after the intervention. Method of measurement: Xerostomia Inventory (XI) questionnaire (11 questions). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Dadashi
Tehran University of Medical Sciences
Outcome results
None listed