Cardiovascular disease. Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Intervention 1: Intervention group 1:Patients who receive three capsules containing 500 mg of curcumin and 5 mg of piperine per day for 5 days. Intervention 2: Intervention group 2: Patients receiving
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age 30-80 years Gastrointestinal normal function and with intestinal or oral nutrition criteria Ejection fraction (EF) above 15% Arrest Time (cardiac resuscitation) 30 to 90 minutes Willingness to participate in the study and complete the consent form before surgery
Exclusion criteria
Exclusion criteria: Allergy to herbal products such as turmeric and pepper Taking herbal supplements (as a supplement) during 3 months before the operation Need for emergency surgery Requires balloon pump Adding another operation in addition to CABG, like simultaneous valve operation Patients who do not have an indication for intestinal or oral nutrition on the first day of the intervention and are expected to be unable to receive intestinal or oral nutrition in the future Patients with a history of underlying disease such as congenital and immune disorders and pancreatitis Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| C reactive Protein (CRP). Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;Blood urea nitrogen (BUN). Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;Creatinine (Cr). Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;Lactate Dehydrogenase (LDH). Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;CK-MB. Timepoint: At baseline and end of the study. Method of measurement: Commercial diagnostic kit.;Troponin. Timepoint: At baseline and end of the study. Method of measurement: Commercial diagnostic kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| 28-days mortality rate. Timepoint: End of the study. Method of measurement: Mathematically dividing the number of dead people by the total number of people using hospital records or telephone follow-up.;Atrial fibrillation. Timepoint: End of the study. Method of measurement: Electrocardiogram (ECG or EKG). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Bagherniya
Esfahan University of Medical Sciences
Outcome results
None listed