Cardiovascular disease. Presence of aortocoronary bypass graft
Conditions
Interventions
Intervention 1: Intervention group: Patients who receive three sachets daily, each containing 10 grams of trehalose purchased from Shaanxi Fruiterco Biotechnology Co., Ltd. China, for 5 days (total of
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Non-emergency coronary artery bypass surgery Age 30-80 years Gastrointestinal normal function and with intestinal or oral nutrition criteria Ejection fraction (EF) above 30% Arrest Time (cardiac resuscitation) 30 to 90 minutes Willingness to participate in the study and complete the consent form before surgery
Exclusion criteria
Exclusion criteria: Taking herbal supplements (as a supplement) during 3 months before the operation Requires balloon pump Adding another operation in addition to coronary artery bypass surgery(CABG), like simultaneous valve operation Patients with a history of underlying disease such as congenital and immune disorders and pancreatitis Diabetic patients who require insulin injections to control blood sugar or have uncontrolled diabetes. Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| C reactive Protein (CRP). Timepoint: At baseline (before the start of the intervention) and on the fifth day (end of the intervention). Method of measurement: ELISA test.;Lactate Dehydrogenase (LDH). Timepoint: At baseline (before the start of the intervention) and on the fifth day (end of the intervention). Method of measurement: ELISA test.;Interleukin 6 (int-6). Timepoint: At baseline (before the start of the intervention) and on the fifth day (end of the intervention). Method of measurement: ELISA test.;Creatine Kinase-MB. Timepoint: At baseline (before the start of the intervention) and on the fifth day (end of the intervention). Method of measurement: ELISA test.;Atrial fibrillation. Timepoint: On the fifth day (end of the intervention). Method of measurement: Electrocardiogram (ECG or EKG). | — |
Secondary
| Measure | Time frame |
|---|---|
| 28-days mortality rate. Timepoint: 28 days after coronary artery bypass surgery. Method of measurement: Mathematically dividing the number of dead people by the total number of people using hospital records or telephone follow-up.;Fasting Blood Sugar. Timepoint: At baseline (before the start of the intervention) and on the fifth day (end of the intervention). Method of measurement: Photometric.;Cell Blood Count. Timepoint: At baseline (before the start of the intervention) and on the fifth day (end of the intervention). Method of measurement: Auto hematology analyzers. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Bagherniya
Esfahan University of Medical Sciences
Outcome results
None listed