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effect of olive leaf extract on Covid-19 patients

The effect of alcoholic extract of the olive leaf on clinical and Laboratory outcomes of patients with Covid-19

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201128049520N1
Enrollment
129
Registered
2021-02-22
Start date
2021-03-05
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID - 19. Coronavirus infection, unspecified

Interventions

Intervention 1: Intervention group: Patients who at the same time with standard treatments, capsules containing olive leaf extract (capsules with a dose of 250 mg twice a day for five days) olive leaf

Sponsors

Khoram-Abad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: All patients with Quid-19 based on standard diagnostic test (positive PCR test, CT scan of lung) approved by infectious disease specialist Age range is 18 to 70 years Have a level of consciousness of 15 according to the Glasgow standard

Exclusion criteria

Exclusion criteria: Take oleopurine supplements 3 months before the study Use of mechanical ventilation equipment Existence of underlying respiratory diseases such as COPD, asthma Taking anti-hypertensive, anti-platelet and anti-diabetic drugs Pregnancy and lactation Immune system deficiency or the use of immunosuppressive drugs Malignancies Presence of heart, kidney, liver, blood pressure, diabetes and corticosteroid disorders Reluctance to continue cooperation The patient is discharged earlier than the completion of the treatment period Hypotension (mean arterial pressure less than 70 mm Hg) Hypoglycemia (blood sugar less than 75 mg / dL) Existence of allergies to drugs before and during the study Lack of proper use of drugs The need for therapeutic interventions other than the usual therapeutic interventions during research such as the need for dialysis, angioplasty and ... Participate in other research that in any way affects the results of the research

Design outcomes

Primary

MeasureTime frame
Arterial oxygen saturation. Timepoint: Before starting the intervention, then for five days twice a day from 6 am to 6 pm. Method of measurement: Medair pulse oximeter device.;Heart rate. Timepoint: Before starting the intervention, then for five days twice a day from 6 am to 6 pm. Method of measurement: pulse oximeter device.;Temperatures. Timepoint: Before starting the intervention, then for five days twice a day from 6 am to 6 pm. Method of measurement: Digital thermometer.;Blood pressure. Timepoint: Before starting the intervention, then for five days twice a day from 6 am to 6 pm. Method of measurement: Hand pressure gauge.;Complete blood count. Timepoint: Before and during the intervention on a daily basis. Method of measurement: Patient file.

Secondary

MeasureTime frame
Severity of general symptoms of Covid-19 disease. Timepoint: Before and during the intervention on a daily basis. Method of measurement: Symptom Severity Questionnaire.;Duration of hospitalization. Timepoint: Patient discharge time. Method of measurement: Counting the number of days the patient is hospitalized.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Ahmadpour

Khoram-Abad University of Medical Sciences

elhamahmadpour10@gmail.com+98 66 3341 3823

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026